Future University In Egypt (FUE)
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Egypt
Faculty of Engineering & Technology
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Staff Researches

Synthesis of novel 2,3- disubstituted quinazoline- 4(3H) ones and their effect on the ultrastructure of some pathogenic microorganisms

  • Author Name :
    Salwa Abdelwahhab
  • CoAuthors :
    MAHMOUD. M.Ra, SALWA.S. ABD EL WAHABb.
  • Source :
    Egyptian journal of chemistry
  • Research Date :
    01/2017
  • Abstract :
    A series of highly functionalized hitherto unreported quinazolinones with different substituent at position 3 have been concisely synthesized in good yields via the reaction of 3-amino-6-bromo-2-undecylquinazoline-4(H)one with one carbon donor such as phenylisothiocyanate, α- halogenated compounds and chloroacetylchloride. Moreover, the reaction of 6-bromo-2-undecylbenzoxazin-4(H)onewith different hydrazides and 2-aminothiophenol was also investigated.The structures of all new synthesized compounds in this investigation were determined using spectroscopic tools (IR, 'HNMR, MS and 13C-NMR).
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