Author : Mohamed Mohamed
CoAuthors : Samah S Abbas, Nour E Wagieh, Maha M Abdelrahman
Source : Journal of AOAC International
Date of Publication : 01/2011
Abstract :
Three methods are presented for the simultaneous determination of diloxanide furoate
(DLX) and metronidazole (MTR), used for their antiprotozoal and antiamoebic effect, in the
presence of DLX alkaline degradates and in pharmaceutical formulations, without previous
separation. The first method is chemometric-assisted spectrophotometry, in which principal
component regression and partial least squares were applied. These two approaches were
successfully applied to quantify each drug in the mixture using the information included in ...
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