Future University In Egypt (FUE)
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Marwa Shabayek

Basic information

Name : Marwa Shabayek
Title: Associate Professors at the Biochemistry section-pharmacology,Toxicology and Biochemistry Department
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Personal Info: Dr/Marwa Ismail Shabayek,Biochemistry section-Pharmacology,Toxicology and Biochemistry Department.She got her Master and Doctoral degrees From Cairo University.

Education

Certificate Major University Year
PhD Biochemistry Cairo University - Faculty of Pharmacy 2009
Masters Biochemistry Cairo University 2006
Bachelor . Ain Shams University - Faculty of Pharmacy 2000

Teaching Experience

Name of Organization Position From Date To Date
Future University in Egypt Lecturer of Biochemistry 01/01/2010 01/01/2016
National Organization of Drug Control & Research / El Doah Hospital Researcher / laboratory specialist (managing PCR unit) 01/01/2001 30/05/2009

Researches /Publications

Non Classical Antifolates, Part 5. Benzodiazepine Analogs as a New Class of DHFR Inhibitors: Synthesis, Antitumor Testing and Molecular Modeling Study - 01/0

Marwa Ismail Abdellatif Abou Shabayek

01/01/2014

A new series of tetrahydro quinazoline and tetrahydro 1H dibenzo diazepine analogs were synthesized and tested for their DHFR inhibition and in vitro antitumor activity. Compound 35 showed a remarkable DHFR inhibitory potency which is twenty fold more active than methotrexate (MTX). Compounds 17 and 23 proved to be fifteen fold more active than the known antitumor 5 FU, with MG MID GI50, TGI and LC50 values of 1.5, 46.8, 93.3 and 1.4, 17.4, 93.3 respectively. Computer modeling studies allowed the identification that methoxy and methyl substituents, the system of the chalcone core, the nitrogen atoms, on the dibenzodiazepine ring as pharmacophoric features essential for activity. These mark points could be used as template model for further future optimization.

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Calcium homeostasis in progression of diabetic nephropathy - 01/0

Marwa Ismail Abdellatif Abou Shabayek

01/01/2012

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- International Conference on Pharmaceutical Technology, Future University (2011). - 01/0

Marwa Ismail Abdellatif Abou Shabayek

01/01/2011

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Diagnostic evaluation of apoptosis inhibitory gene and tissue inhibitor matrix metalloproteinase-2 in patients with bladder cancer - 01/0

Marwa Ismail Abdellatif Abou Shabayek

01/01/2010

Diagnostic evaluation of apoptosis inhibitory gene and tissue inhibitor matrix metalloproteinase-2 in patients with bladder cancer ; Sanaa Eissa, Marwa I. Shabayek, Manal F. Ismail, Raouf M. El-Allawy, and Mohamed A. Hamdy ;IUBMB Life ;62 (2), 394-399

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Awards

Award Donor Date
PhD practical work was apart of project no.21 supported by the Academy of Scientific Research and Technology, Technology Development and Scientific Sector, Science and Technology Center, Egypt. Academy of Scientific Research and Technology 2006
Masters degree practical work was apart of project no.21 supported by the Academy of Scientific Research and Technology, Technology Development and Scientific Sector, Science and Technology Center, Egypt Academy of Scientific Research and Technology 2002

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